Bento Games has won many awards for the concept of its unWorded, a narrative tale that's pretty strange even by modern indie standards. According to the game's site, the story is about a book writer, who was hospitalised after a serious accident. As his wife at his bedside reads fairy tales of his own creation, the player is in his mind, sharing his last thoughts as he reminisces about his life and work, standing with him at the death's door.
The game is mentioned for Vita, after the iOS release, I'm checking with the developer for any details. It is developed in Unity, but doesn't seem to be doing anything that would overly tax the Vita hardware.